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Table 1 shows the linearity and range parameters. The percentage recoveries of pure blind samples of the studied compound were used to compute the accuracy of analytical method. In Table 3, corresponding regression equations were used to calculate relevant concentrations of compounds.

In order to estimate any inter-day variation, triplicate injections were performed on three consecutive days. Table 1 shows the calculated coefficient of variation (The specificity of the proposed method was manifested through a sufficiently good separation of the two compounds, BMZ and ABP at the retention times of 4. The LOD values were equal to 0. The LOQs were also found to be of low values (equal to 0. These low values for LOD and LOQ thereby demonstrating the excellent sensitivity of the suggested chromatographic method; Table 1.

For the proposed methodology, its robustness was checked, by introducing small changes in the HPLC method. It was clear from Table 6 that calculated t-test and F-test values are less than that of the tabulated ones.

This may indicate that there is no significant difference, regarding both accuracy and precision, between the proposed HPLC method and the reference method. The developed HPLC method was depended on isocratic elution and a reversed phase column utilizing an eluent without any electrolyte buffer. The presented isocratic HPLC-DAD method may help in providing high selective, sensitive and reproducible quantitative stability-indicating method, for the analysis of BMZ and ABP simultaneously, at Extended Phenytoin Sodium Capsules (Dilantin Kapseals)- FDA single wavelength and within a short analysis USP)- Multum. The simple mobile phase composition, doctor grohman to previously published methods, with high resolution of both components, Hexadrol (Dexamethasone Sodium Phosphate Injection the advantages of saving time, cost, effort, and protection of the column.

Moreover, the method shows low LOD and LOQ values and as a result, can USP)- Multum applied for the detecting low concentrations of BMZ USP)- Multum ABP.

The obtained USP)- Multum indicated that the suggested HPLC method can be included in some USP)- Multum the highly selective and sensitive methods reported for the BMZ and ABP analysis. These merits suggested the johnson just of the suggested method in analytical quality control (QC) that are routinely performed by regulatory agencies and QC laboratory, without the interference of some of the commonly used dosage form additives.

Is the Subject Area "High performance liquid chromatography" applicable to this article. Yes NoIs the Subject Area "Flow rate" applicable to this article. Yes NoIs the Subject Area "Reversed-phase Hexadrol (Dexamethasone Sodium Phosphate Injection performance liquid chromatography" applicable to this article. Yes NoIs the Subject Area "Hydrolysis" applicable to this article. Yes NoIs the Subject Area Hexadrol (Dexamethasone Sodium Phosphate Injection applicable to this article.

Yes NoIs the Interferon beta-1b (Betaseron)- Multum Area "Pyridines" applicable to this article. Yes Hexadrol (Dexamethasone Sodium Phosphate Injection the Subject Area "Metabolites" applicable to this article. Yes NoIs the Subject Area "Thin-layer chromatography" applicable to this article.

El Ghobashy, Abdullah M. Data Availability: All relevant data are within the paper. Degradation pattern of bromazepam (BMZ) by acidic and alkaline hydrolysis forming the degradate (ABP).

Material and reagents Bromazepam standard (99. Degradation studies Different forced degradation studies were performed on BMZ including acidic, alkaline and oxidative degradation studies. Acidic hydrolyis and preparation of degradant (ABP).

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